Can I use Panther version to clone Tiger drive?
 

I've got three different operating systems (well, four if you count OS 9) on 3 internal drives (I never throw anything out);)

So as not to be backing up active processes, I usually boot from a drive other than the source drive. Is it OK to boot in Panther and use SuperDuper! 2.1.4 to clone my Tiger volume?

If you must, it should work... but in general I don't suggest using earlier OS version to copy later OS disks.